ncRNA name | mmu-miR-30a-5p |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Mus musculus |
Tissues/Cell_line | retinas |
Methods | immunofluorescence, in situ hybridization, qPCR, flow cytometry |
Expression pattern | up-regulated |
Functional description | miR-30a-5p inhibition accelerates tissue repair by enhancing FasL-Fas crosstalk between microglia and endothelial cells, to promote endothelial cell apoptosis and removal of dead endothelial cells. |
PubMed ID | 30484883 |
Year | 2019 |
Title | miR-30a-5p inhibition promotes interaction of Fas+ endothelial cells and FasL+ microglia to decrease pathological neovascularization and promote physiological angiogenesis. |
Drug-related ncRNA | NO |
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