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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name mmu-miR-30a-5p
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Mus musculus
Tissues/Cell_line retinas
Methods immunofluorescence, in situ hybridization, qPCR, flow cytometry
Expression pattern up-regulated
Functional description miR-30a-5p inhibition accelerates tissue repair by enhancing FasL-Fas crosstalk between microglia and endothelial cells, to promote endothelial cell apoptosis and removal of dead endothelial cells.
PubMed ID 30484883
Year 2019
Title miR-30a-5p inhibition promotes interaction of Fas+ endothelial cells and FasL+ microglia to decrease pathological neovascularization and promote physiological angiogenesis.
Drug-related ncRNA NO

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